Buy DERMOVATE CREAM 0.05% 25g 1 tube


Active substance: clobetasol propionate


Without prescription
1 tube x 25 grams



Dermovate is a very potent topical glucocorticosteroid indicated for the short-term treatment of symptoms of inflammation and pruritus in dermatoses that are sensitive to glucocorticosteroid therapy and for those refractory to less potent glucocorticosteroids (for adults, the elderly and children over 1 year of age).

Clobetasol propionate prevents marginal accumulation of neutrophils, reduces inflammatory exudation and production of lymphokines, inhibits the migration of macrophages, reduces the intensity of infiltration and granulation processes, has local anti-inflammatory, antipruritic, anti-allergic and anti-exudative effects.

Indications for use of Dermovate cream 

Dermovate cream is used in the treatment of various forms of dermatoses, accompanied by inflammatory reactions, itching and other characteristic symptoms and is prescribed in the absence of the effectiveness of other drugs related to NSAIDs.

lesion with psoriasis, excluding the plaque form of the disease; 

different types and types of eczema; 

lupus erythematosus (discoid); 

refractory dermatoses; 

lichen planus; 

other skin pathologies that cannot be treated with less active topical steroid preparations.


Contraindications for use of Dermovate

Acne rosacea;

Acne vulgaris;

Skin cancer;

Hyde's nodular pruritus;

Perioral dermatitis;

Perianal and genital itching;

Bacterial, viral and fungal skin diseases (herpes simplex, chickenpox, skin tuberculosis, actinomycosis, etc.);

Widespread plaque and pustular psoriasis;

Hypersensitivity to the active and auxiliary substances of the drug;

Age up to 1 year;

Lactation period.

The use of Dermovate cream during pregnancy and during breastfeeding

There is insufficient data on the use of clobetasol in pregnant women.

According to data from preclinical studies, clobetasol can negatively affect the development of the fetus.

The significance of these data to humans has not been studied.

The drug should be used during pregnancy only if the intended benefit to the mother outweighs the potential risk to the fetus.

In the case of prescribing the drug during pregnancy, the minimum amount of ointment should be used for the shortest possible time.

The use of the drug during breastfeeding is contraindicated.

Method of administration and dose of Dermovate cream or ointment

Demovate ointment or cream should be applied in a thin layer to the affected skin 1-2 times / day until improvement occurs. The course of treatment is no more than 4 weeks. The doctor determines the need for a longer course individually.

For the treatment of exacerbations of skin diseases, short repeated courses can be carried out.

If it is necessary to continue therapy with corticosteroids, then less active drugs should be used.

In particularly resistant cases, especially in the presence of hyperkeratosis, the anti-inflammatory effect of Dermovate ointment and cream can be enhanced by applying a plastic film bandage to the area of ​​application of the drug at night, which is usually accompanied by a positive effect. In the future, the achieved effect can be maintained without the use of an occlusive dressing.

Side effects of Dermovate

From the endocrine system: long-term administration of GCS for external use in high doses or their application to large areas of the skin may be accompanied by systemic absorption with the subsequent development of symptoms of hypercortisolism. The risk of developing this complication is increased in children, especially when using an occlusive dressing, while the diaper can act as such a dressing.

Provided that Dermovate is prescribed to adult patients at a dose of no more than 50 g per week, the suppression of the function of the pituitary and adrenal glands has a transient nature with their rapid recovery immediately after the end of the course of treatment.

Dermatological reactions: long-term treatment with highly active GCS for external use in high doses can cause atrophic changes in the skin, in particular its thinning, the appearance of atrophic streaks (striae), dilatation of superficial blood vessels, especially when applying occlusive dressings and when applying the drug to areas of skin with folds.

Possible - skin pigmentation and hypertrichosis.

In rare cases, treatment of psoriasis with GCS for external use (or their cancellation) provokes the development of pustular psoriasis.

Sometimes Dermovate causes an exacerbation of the symptoms of the disease.

Overdose of Dermovate cream

Symptoms: Dermovate ointment or cream, when applied externally, can be absorbed in quantities sufficient to cause the development of systemic effects.

The development of an acute overdose is unlikely. However, in the case of chronic overdose or improper use of the drug Dermovate, symptoms of hypercortisolism may develop.

Treatment: in case of an overdose of clobetasol propionate, cream should be gradually canceled, reducing the frequency of application or replacing it with less active GCS, under the supervision of a doctor due to the risk of adrenal insufficiency.

Further treatment should be guided by the clinical situation or as recommended by poison control centers, if available.

Special instructions

Please refer to the instructions page.

Dermovate cream for sale:  Even if a prescription is not required, it is assumed that you have a valid prescription or doctor's recommendation. Please do not self-medicate. Please consult an expert before purchasing Dermovate cream.

The product you are ordering, Dermovate cream, is intended for Russian market and can be labeled in Russian (Packaging design may vary). 

The drug images are for illustrative purposes only and may differ from the actual product.

To make sure that you are buying the right product, just translate the word Дермовейт into English using Google Translate. Just copy and paste.

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  • Product Code: DV005X25
  • Availability: In Stock
  • $38.98

  • Ex Tax: $38.98